S&P 500 Analysis Sars-cov-2 Variant 501Y Outbreak Starting E-MINI S&P 500 FUTURES (CONTINUOUS: CURRENT CONTRACT IN FRONT) CME_MINI:ES1! btcsun S&P 500 Analysis Sars-cov-2 Variant 501Y Outbreak Starting, Ultra Tier Lockdowns, Small business Shutdowns, World Government Bureaucracy refusing to allow the free markets to cure or inhibit sars-cov-2 with Natural Products, or other Safe Pharmaceuticals that are researched and have been researched in various medical journals Does the s&p 500 continue the K shaped recovery? Or will we see markets profit take ahead of this 501Y variant, and use the news of the Variant Mutation to continue the sell off. Defining mutations: Has appeared multiple times independently: each can be associated with different accompanying mutations Amino-acid changes are N501Y (nucleotide mutation A23063T), N501T (nucleotide mutation A23064C), and N501S (nucleotide mutation A23064G) S:N501 Mutation is in the receptor binding domain (RDB), important to ACE2 binding and antibody recognition N501Y is associated with a recently reported 'new variants' in the UK and South Africa: '20B/501Y.V1' (B.1.1.7) was announced in the South East of England on 14 Dec 2020 (COG-UK Report, Rambaut et al., PHE report) This particular variant is associated with multiple mutations in Spike, including: N501Y, a deletion at 69/70 (as seen in S:N439K & S:Y453F) (Kemp et al. bioRxiv (21 Dec)), Y144 deletion, and P681H (adjacent to the furin cleavage site). There is also a notable truncation of ORF8, with Q27* (becomes a stop codon), and mutations in N: N:D3L and S235F. '20C/501Y.V2' is found in South Africa and was also announced in December 2020 (Tegally et al., medRxiv) This variant is associated with multiple mutations in Spike, including: N501Y, K417N, and D80A. There is also an N mutation: T205I. It does not have the deletion at 69/70. https://github.com/emmahodcroft/covariants/blob/master/READM... https://www.nature.com/articles/s41598-020-74715-4 Molecular docking study of potential phytochemicals and their effects on the complex of SARS-CoV2 spike protein and human ACE2